名称：重组人4-1BB Ligand/4-1BBL/TNFSF9/CD137LProtein（N-Fc）；

产品说明(Description)
Recombinant Human 4-1BB Ligand is produced by our Mammalian expression system and the target gene encoding Arg71-Glu254 is expressed with a Fc tag at the N-terminus. 
Accession #: P41273
Known as: Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL; TNFSF9

制剂（Formulation）
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

质量控制（Quality Control） 
Purity:Greater than 95% as determined by reducing SDS-PAGE.    
Endotoxin:Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

复溶（Reconstitution）
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

保存（Storage）
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.    

背景（Background）
Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.

电泳(SDS-PAGE)

FOR RESEARCH USE ONLY