名称:重组Exendin-4
Synonyms:Exenatide
Accession:P26349
Source:Escherichia coli.
Molecular Weight:Approximately 4.2 kDa, a single non-glycosylated polypeptide chain containing 39 amino acids.
Quantity:20μg/100μg/1000μg
AA Sequence:HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS
Purity:> 96 % by SDS-PAGE and HPLC analyses.
Biological Activity:1. Regulates Glucose levels rapidly;
2. Reduces Insulin resistance;
3. Reduces Glucagon;
4. Reduces HbA1c;
5. Stimulates beta cell growth which stimulates insulin production.
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Endotoxin:Less than 10 EU/mg of rExendin-4 as determined by LAL method.
Reconstitution:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Stability & Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
SDS-PAGE: